Chemical Name:Abacavir Triphosphate TEA Salt
Mol.Formula:C14H21N6O10P3 • xC6H15N
Application Notes:Abacavir Triphosphate TEA Salt, is a metabolite of Abacavir. Abacavir is a carbocyclic 2-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Melting Pt.:>104C (dec.)
Boiling Pt.:No Data Available
Solubility:No Data Available
Storage Condition:Hygroscopic, -20°C Freezer, Under inert atmosphere
Shiping Info:Blue Ice